Table 1

Patient Characteristics According to the Treatment Group

RangeSimvastatin 80 mg (n = 22)Simvastatin 20 mg (n = 29)p Value
Age (yrs)41.4–82.962.6 ± 7.662.3 ± 10.0NS
BMI (kg/m2)18.8–34.826.5 ± 3.225.1 ± 3.7NS
TC (mg/dl)193–356257 ± 38241 ± 39.0089
LDL-C (mg/dl)110–226173 ± 33154 ± 31.0005
HDL-C (mg/dl)26–12657.0 ± 19.555.6 ± 20.7NS
TG (mg/dl)41–600164 ± 84163 ± 116NS
Aortic lesions
 Lumen (mm2)251–1,092464 ± 170425 ± 149NS
 TVA (mm2)417–1,790749 ± 236744 ± 267NS
 VWA (mm2)145–884285 ± 80319 ± 176NS
Carotid lesions
 Lumen (mm2)9.2–73.632 ± 1133 ± 14NS
 TVA (mm2)43.0–151.679.1 ± 20.280.4 ± 26.1NS
 VWA (mm2)26.5–86.948.6 ± 12.647.8 ± 16.4NS

BMI = body mass index; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; TC = total cholesterol; TG = triglycerides; TVA = total vessel area; VWA = vessel wall area.

  • To convert values to millimoles per liter, multiply by 0.02586.

  • Significant differences between the treatment groups (20 mg vs. 80 mg) are tested by unpaired ttest. Data are given as mean ± SD.