Table 6

Comparison of Hemodynamics at Diagnosis in Different PAH Subgroups and in Pre-Capillary PH Associated With SCD

HemodynamicIPAH (43)
(n = 288)
CTD-PAH (43)
(n = 157)
POPH (43)
(n = 127)
CHD-PAH (43)
(n = 35)
HIV-PAH (38)
(n = 58)
PH-SCD (43,56)
(n = 11)
RAP, mm Hg8 ± 57 ± 58 ± 67 ± 58 ± 55 ± 2
mPAP, mm Hg49 ± 1341 ± 947 ± 1251 ± 1649 ± 1028 ± 4
PCWP, mm Hg9 ± 48 ± 49 ± 048 ± 49 ± 510 ± 3
Cardiac index, l/min/m22.4 ± 0.82.8 ± 0.93.0 ± 1.03.0 ± 1.02.9 ± 0.75.8 ± 1.3
PVR, dyn·s·cm−5831 ± 461649 ± 379611 ± 311753 ± 370737 ± 328178 ± 55

Values are mean ± SD.

CHD = congenital heart disease; CTD = connective tissue disorders; HIV = human immunodeficiency virus; IPAH = idiopathic pulmonary arterial hypertension; mPAP = mean pulmonary artery pressure; PCWP = pulmonary capillary wedge pressure; PH = pulmonary hypertension; POPH = portopulmonary hypertension; PVR = pulmonary vascular resistance; RAP = right atrial pressure; SCD = sickle cell disease.