Table 5

Hemodynamic Characteristics in Patients With PH Associated With SCD in 3 Different Cohorts: France, Brazil, and United States

CharacteristicFrench Cohort (56)
(n = 24)
Brazilian Cohort (57)
(n = 8)
U.S. Cohort (62)
(n = 56)
RAP, mm Hg10 ± 610 ± 5
mPAP, mm Hg30 ± 633.1 ± 8.936 ± 9
PCWP, mm Hg16 ± 716.0 ± 5.716 ± 5
CO, l/min–CI, l/min/m28.7 ± 1.95.00 ± 1.368 ± 3
PVR, dyn·s·cm−5138 ± 58179 ± 120229 ± 149

CI = cardiac index; CO = cardiac output; mPAP = mean pulmonary artery pressure; PCWP = pulmonary capillary wedge pressure; PH = pulmonary hypertension; PVR = pulmonary vascular resistance; RAP = right atrial pressure; SCD = sickle cell disease.

  • Cardiac index use instead of cardiac output in the Brazilian cohort.