Table 5

Changes in Mean BP and Mean LDL-C Over 9 Months for Polypill Treatment and Control Groups, Phase 2

ControlPolypillp Value
Intention-to-treat
 ΔSBP, mm Hg0.88 (−0.76 to 2.53)−0.32 (−2.02 to 1.38)0.32
 ΔDBP, mm Hg0.38 (−0.69 to 1.46)−0.11 (−1.13 to 0.90)0.51
 ΔLDL-C, mg/dl2.17 (−0.96 to 5.29)5.27 (−0.31 to 10.86)0.34
Per-protocol
 ΔSBP, mm Hg0.63 (−1.47 to 2.74)−0.97 (−3.15 to 1.21)0.30
 ΔDBP, mm Hg0.49 (−0.86 to 1.85)−0.58 (−1.91 to 0.74)0.27
 ΔLDL-C, mg/dl2.90 (−1.15 to 6.95)5.13 (−2.97 to 13.24)0.64

Values are change in BP and LDL cholesterol, given in mm Hg and mg/dl.

BP = blood pressure; LDL = low density lipoprotein; other abbreviations as in Table 1.