Table 7

Comparison of the CHADS2 and CHA2DS2-VASc Risk Stratification Scores for Subjects With Nonvalvular AF

Definition and Scores for CHADS2 and CHA2DS2-VAScStroke Risk Stratification With the CHADS2 and CHA2DS2-VASc Scores
ScoreAdjusted Stroke Rate (% per y)
CHADS2CHADS2
 Congestive HF101.9
 Hypertension112.8
 Age ≥75 y124.0
 Diabetes mellitus135.9
 Stroke/TIA/TE248.5
 Maximum score6512.5
618.2
CHA2DS2-VAScCHA2DS2-VASc
 Congestive HF100
 Hypertension111.3
 Age ≥75 y222.2
 Diabetes mellitus133.2
 Stroke/TIA/TE244.0
 Vascular disease (prior MI, PAD, or aortic plaque)156.7
 Age 65–74 y169.8
 Sex category (i.e., female sex)179.6
 Maximum score986.7
915.20

AF indicates atrial fibrillation; CHADS2, Congestive heart failure, Hypertension, Age ≥75 years, Diabetes mellitus, Prior Stroke or TIA or Thromboembolism (doubled); CHA2DS2-VASc, Congestive heart failure, Hypertension, Age ≥75 years (doubled), Diabetes mellitus, Prior Stroke or TIA or thromboembolism (doubled), Vascular disease, Age 65 to 74 years, Sex category; HF, heart failure; MI, myocardial infarction; PAD, peripheral artery disease; TE, thromboembolism; and TIA, transient ischemic attack (202,203).

  • These adjusted stroke rates are based on data for hospitalized patients with AF and were published in 2001 (201). Because stroke rates are decreasing, actual stroke rates in contemporary nonhospitalized cohorts might vary from these estimates.

  • Adjusted stroke rate scores are based on data from Lip and colleagues (15,30,171,202,203). Actual rates of stroke in contemporary cohorts might vary from these estimates.