Table 2

Baseline Angiographic and Procedural Characteristics According to the Occurrence of IPST

IPST (n = 89)No IPST (n = 10,850)p Value
Number of vessels with stenosis >50%
 00/89 (0.0)3/10,832 (0.0)0.39
 138/89 (42.7)5,255/10,832 (48.5)
 225/89 (28.1)3,245/10,832 (30.0)
 317/89 (19.1)1,691/10,832 (15.6)
 >39/89 (10.1)638/10,832 (5.9)
Number of vessels per patient undergoing PCI during the Index procedure
 00/89 (0.0)98/10,850 (0.9)0.009
 170/89 (78.7)9,076/10,850 (83.6)
 214/89 (15.7)1,477/10,850 (13.6)
 34/89 (4.5)188/10,850 (1.7)
 >31/89 (1.1)11/10,850 (0.1)
Vessels treated
 Right coronary artery29/89 (32.6)3,884/10,850 (35.8)0.53
 Left anterior descending artery51/89 (57.3)5,368/10,850 (49.5)0.14
 Left circumflex artery28/89 (31.5)3,117/10,850 (28.7)0.57
 Left main6/89 (6.7)269/10,850 (2.5)0.011
Drug-eluting stent(s) implanted47/89 (52.8)6,033/10,850 (55.6)0.60
Bare metal stent(s) implanted50/89 (56.2)4,601/10,850 (42.4)0.009
Total stent length implanted (mm)37.0 (23.0–59.0)23.0 (16.0–36.0)<0.0001
Time from study drug administration to start of PCI (min)4 (2–8)4 (2–8)0.99
Duration of PCI (min)37.0 (21–60)17.0 (10–30)<0.0001
Patients with IVUS-guided PCI6/89 (6.7)605/10,850 (5.6)0.63
Pre-TIMI flow grade0.005
 018/89 (20.2)1,694/10,727 (15.8)
 18/89 (9.0)386/10,727 (3.6)
 213/89 (14.6)1,041/10,727 (9.7)
 350/89 (56.2)7,606/10,727 (70.9)
Post-TIMI flow grade<0.0001
 06/88 (6.8)87/10,542 (0.8)
 17/88 (8.0)92/10,542 (0.9)
 26/88 (6.8)356/10,542 (3.4)
 369/88 (78.4)10,007/10,542 (94.9)
Lesion length15.9 (11.4–24.3)13.1 (9.4–19.3)0.0007
Thrombus at baseline38/89 (42.7)2,562/10,740 (23.9)<0.0001
 Thrombus area (mm2)17.7 (10.5–28.6)13.2 (8.1–21.4)0.28
Tortuosity Moderate or Severe6/89 (6.7)319/10,718 (3.0)0.04
Calcification0.99
 None/mild66/89 (74.2)7,948/10,657 (74.6)
 Moderate18/89 (20.2)2,133/10,657 (20.0)
 Severe5/89 (5.6)576/10,657 (5.4)

Values are n/N (%) or median (interquartile range).

IPST = intra-procedural stent thrombosis; IVUS = intravascular ultrasound; PCI = percutaneous coronary intervention; TIMI = Thrombolysis In Myocardial Infarction.