Table 1

Baseline Clinical Characteristics According to the Occurrence of IPST

CharacteristicIPST
(n = 89)
No IPST
(n = 10,850)
p Value
Age (yrs)63.0 (55–74)64.0 (56–72)0.76
Female31/89 (34.8)3,019/10,850 (27.8)0.14
Body mass index (kg/m2)28.1 (25.4–31.6)28.4 (25.6–31.8)0.43
Medical history
 Diabetes mellitus26/89 (29.2)3,028/10,835 (27.9)0.79
 Current smoker33/86 (38.4)3,020/10,589 (28.5)0.04
 Hypertension69/89 (77.5)8,635/10,821 (79.8)0.60
 Hyperlipidemia54/78 (69.2)6,647/9606 (69.2)0.99
 Prior stroke/TIA4/89 (4.5)511/10,815 (4.7)0.92
 Prior MI19/85 (22.4)2,248/10,784 (20.8)0.73
 Prior PTCA/PCI15/88 (17.0)2,586/10,832 (23.9)0.13
 Prior CABG9/88 (10.2)1,069/10,839 (9.9)0.91
 History of CHF8/88 (9.1)1,128/10,825 (10.4)0.68
 History of peripheral artery disease11/89 (12.4)821/10,734 (7.6)0.10
Region0.04
 United States24/89 (27.0)4,073/10,850 (37.5)
 Non-U.S.65/89 (73.0)6,777/10,850 (62.5)
Patient presentation0.0006
 NSTE-ACS33/89 (37.1)2,777/10,850 (25.6)
 Stable angina32/89 (36.0)6,106/10,850 (56.3)
 STEMI24/89 (27.0)1,967/10,850 (18.1)
Baseline cardiac biomarkers<0.0001
 Normal38/89 (42.7)6,912/10,841 (63.8)
 Abnormal51/89 (57.3)3,929/10,841 (36.2)
Periprocedural medications
 Aspirin87/89 (97.8)10,022/10,842 (94.3)0.16
 Unfractionated heparin67/89 (75.3)7,459/10,849 (68.8)0.19
 Clopidogrel loading dose 600 mg58/89 (65.2)8,075/10,850 (74.4)0.047
 Clopidogrel loading dose 300 mg31/89 (34.8)2,775/10,850 (25.6)0.047
 Glycoprotein IIb/IIIa inhibitor31/89 (34.8)349/10,850 (3.2)<0.0001
 Bivalirudin18/89 (20.2)2,463/10,848 (22.7)0.58
 Low molecular weight heparin4/89 (4.5)509/10,848 (4.7)0.93
 Fondaparinux0/89 (0)31/10,849 (0.3)0.61
Catheter access site0.29
 Femoral72/89 (80.9)7,992/10,850 (73.7)
 Radial17/89 (19.1)2,835/10,850 (26.1)
 Brachial0/89 (0)23/10,850 (0.2)
Length of stay (randomization to discharge, h)45.6 (26.2–136.2)27.0 (23.0–51.1)<0.0001

Values are median (interquartile range) or n/N (%).

CABG = coronary artery bypass grafting; IPST = intra-procedural stent thrombosis; NSTE-ACS = non–ST-segment elevation acute coronary syndrome; PCI = percutaneous coronary intervention; PTCA = percutaneous transluminal coronary angioplasty; STEMI = ST-segment elevation myocardial infarction.