Table 3

Landmark Analysis at 30 Days

Intracoronary AbciximabIntravenous AbciximabHR (95% CI)p Valuep Value for Interaction Early vs. Late Period
Diabetes241232
 Death
 Early (0–30 days)9 (3.7)14 (6.0)0.62 (0.27–1.44)0.270.50
 Late (31–365 days)7 (2.2)12 (5.5)0.38 (0.13–1.10)0.074
 Overall (0–365 days)16 (5.8)26 (11.2)0.51 (0.26–0.98)0.043
 Reinfarction
 Early (0–30 days)5 (2.2)8 (3.9)0.58 (0.19–1.78)0.340.79
 Late (31–365 days)4 (1.9)7 (3.7)0.47 (0.13–1.61)0.23
 Overall (0–365 days)9 (4.0)15 (7.5)0.53 (0.23–1.21)0.13
 Death or reinfarction
 Early (0–30 days)12 (5.2)22 (10.0)0.51 (0.25–1.03)0.060.85
 Late (31–365 days)11 (4.2)16 (8.4)0.45 (0.20–1.05)0.065
 Overall (0–365 days)23 (9.2)38 (17.6)0.49 (0.28–0.83)0.009
 Definite ST
 Early (0–30 days)1 (0.4)6 (2.6)0.15 (0.02–1.16)0.0690.72
 Late (31–365 days)0 (0.0)1 (0.4)0.32 (0.01–7.88)0.49
 Overall (0–365 days)1 (0.4)7 (3.0)0.13 (0.02–0.99)0.049
 Definite or probable ST
 Early (0–30 days)3 (1.3)8 (3.8)0.34 (0.09–1.26)0.110.72
 Late (31–365 days)0 (0.0)2 (1.0)0.19 (0.01–4.00)0.29
 Overall (0–365 days)3 (1.3)10 (4.8)0.27 (0.08–0.98)0.046
No diabetes1,001996
 Death
 Early (0–30 days)23 (2.3)28 (2.8)0.81 (0.47–1.41)0.460.13
 Late (31–365 days)19 (1.9)11 (1.1)1.67 (0.79–3.54)0.18
 Overall (0–365 days)42 (4.2)39 (3.9)1.06 (0.68–1.64)0.81
 Reinfarction
 Early (0–30 days)18 (1.9)17 (1.9)1.04 (0.53–2.02)0.910.26
 Late (31–365 days)12 (1.4)19 (2.2)0.59 (0.28–1.22)0.16
 Overall (0–365 days)30 (3.3)36 (4.0)0.80 (0.49–1.30)0.37
 Death or reinfarction
 Early (0–30 days)40 (4.3)41 (4.4)0.96 (0.62–1.49)0.860.95
 Late (31–365 days)28 (3.2)28 (3.3)0.94 (0.55–1.59)0.81
 Overall (0–365 days)68 (7.4)69 (7.5)0.95 (0.68–1.33)0.77
 Definite ST
 Early (0–30 days)7 (0.7)9 (0.9)0.76 (0.28–2.06)0.590.62
 Late (31–365 days)0 (0.0)1 (0.1)0.33 (0.01–8.14)0.50
 Overall (0–365 days)7 (0.7)10 (1.0)0.69 (0.26–1.81)0.45
 Definite or probable ST
 Early (0–30 days)17 (1.8)13 (1.4)1.30 (0.63–2.67)0.480.10
 Late (31–365 days)1 (0.1)5 (0.6)0.19 (0.02–1.61)0.13
 Overall (0–365 days)18 (1.9)18 (2.0)0.98 (0.51–1.90)0.96

Values are n or first events (% from Kaplan-Meier estimate), unless otherwise indicated. Risk estimates for cells with 0 events were calculated with the continuity correction method.

CI = confidence interval; HR = hazard ratio; ST = stent thrombosis.