Table 2

Elevated hs-cTnT and Expected Annual Change in hs-cTnT

Visit 2 DBPCross-Sectional Analysis Elevated hs-cTNT (≥14 ng/l)Longitudinal Analysis Adjusted Beta-Coefficients Estimated Additional Annual Change in hs-cTNT, ng/l (95% CI)
n/NAdjusted Odds Ratio (95% CI)p ValueAnnual Change Between Visits 2 and 4p ValueAnnual Change Between Visits 4 and 5p Value
<60 mm Hg39/1,0872.24 (1.22 to 4.10)0.011.46 (0.51 to 2.40)0.002−0.09 (−0.69 to 0.51)0.77
60–69 mm Hg120/3,7281.52 (1.00 to 2.32)0.050.95 (0.28 to 1.61)0.0050.32 (−0.69 to 1.34)0.54
70–79 mm Hg144/4,2491.02 (0.71 to 1.47)0.900.85 (0.27 to 1.44)0.0040.02 (−0.26 to 0.31)0.86
80–89 mm Hg102/1,9021.00 (reference)0 (reference)0 (reference)
90–99 mm Hg36/4871.06 (0.61 to 1.83)0.84−0.73 (−1.47 to 0.01)0.060.26 (−0.07 to 0.60)0.13
≥100 mm Hg14/1121.54 (0.63 to 3.78)0.34−0.99 (−2.58 to 0.58)0.210.43 (−0.32 to 1.18)0.26

Significant values are indicated in bold.

CI = confidence interval; other abbreviations as in Table 1.

  • Adjusted for age, race-center, sex, body mass index, smoking, alcohol intake, SBP, hypertension medication use, diagnosed diabetes, LDL-C, HDL-C, triglycerides, current use of cholesterol-lowering medication, and eGFR.

  • Linear model with generalized estimating equations and inverse probability of attrition weighting.

  • Logistic model for cross-sectional association between DBP and baseline elevated high-sensitivity cardiac troponin T (hs-cTnT).