Visit 2 DBP | Cross-Sectional Analysis Elevated hs-cTNT (≥14 ng/l) | Longitudinal Analysis Adjusted^{∗} Beta-Coefficients† Estimated Additional Annual Change in hs-cTNT, ng/l (95% CI) | |||||
---|---|---|---|---|---|---|---|

n/N | Adjusted^{∗} Odds Ratio‡ (95% CI) | p Value | Annual Change Between Visits 2 and 4 | p Value | Annual Change Between Visits 4 and 5 | p Value | |

<60 mm Hg | 39/1,087 | 2.24 (1.22 to 4.10) | 0.01 | 1.46 (0.51 to 2.40) | 0.002 | −0.09 (−0.69 to 0.51) | 0.77 |

60–69 mm Hg | 120/3,728 | 1.52 (1.00 to 2.32) | 0.05 | 0.95 (0.28 to 1.61) | 0.005 | 0.32 (−0.69 to 1.34) | 0.54 |

70–79 mm Hg | 144/4,249 | 1.02 (0.71 to 1.47) | 0.90 | 0.85 (0.27 to 1.44) | 0.004 | 0.02 (−0.26 to 0.31) | 0.86 |

80–89 mm Hg | 102/1,902 | 1.00 (reference) | — | 0 (reference) | — | 0 (reference) | — |

90–99 mm Hg | 36/487 | 1.06 (0.61 to 1.83) | 0.84 | −0.73 (−1.47 to 0.01) | 0.06 | 0.26 (−0.07 to 0.60) | 0.13 |

≥100 mm Hg | 14/112 | 1.54 (0.63 to 3.78) | 0.34 | −0.99 (−2.58 to 0.58) | 0.21 | 0.43 (−0.32 to 1.18) | 0.26 |

Significant values are indicated in **bold**.

CI = confidence interval; other abbreviations as in Table 1.

↵∗ Adjusted for age, race-center, sex, body mass index, smoking, alcohol intake, SBP, hypertension medication use, diagnosed diabetes, LDL-C, HDL-C, triglycerides, current use of cholesterol-lowering medication, and eGFR.

↵† Linear model with generalized estimating equations and inverse probability of attrition weighting.

↵‡ Logistic model for cross-sectional association between DBP and baseline elevated high-sensitivity cardiac troponin T (hs-cTnT).