Table 2

RV Deformation

Deformation ImagingControls
(n = 84)
Type I
(n = 12)
Type II
(n = 35)
Type III
(n = 37)
p Value
All GroupsMutation Carriers
Onset of shortening, ms52 (25–72)60 (38–76)119 (99–141)218 (128–293)<0.001<0.001
Systolic peak strain, %−24.7 ± 4.8−23.9 ± 5.3−16.4 ± 3.5−5.3 ± 5.3<0.001<0.001
Peak strain, %−25.4 ± 4.9−24.3 ± 5.2−19.4 ± 4.1−9.6 ± 6.8<0.001<0.001
Post-systolic index, %2 (0–4)1 (0–3)15 (8–21)44 (22–78)<0.001<0.001
Onset of shortening >90 ms5 (6)1 (8)30 (86)37 (100)<0.001<0.001
Post-systolic index >10%3 (4)024 (69)32 (86)<0.001<0.001
Systolic peak strain <|–20%|4 (5)029 (83)37 (100)<0.001<0.001
Systolic peak strain <|–10%|00037 (100)<0.001<0.001

Values are median (interquartile range), mean ± SD, or n (%).

Abbreviations as in Table 1.

  • p < 0.05 versus age-and sex-matched controls (Bonferroni correction).