Table A

High-Risk Features for Short-Term Risk of Death or Nonfatal MI in Patients With NSTEMI/UA

At least 1 of the following:
  • History—accelerating tempo of anginal symptoms in preceding 48 hours

  • Character of pain—prolonged ongoing (>20 minutes) rest pain

  • Clinical findings

    • Pulmonary edema, most likely due to ischemia

    • New or worsening MR murmur

    • S3 or new/worsening rales

    • Hypotension, bradycardia, tachycardia

    • Age >75 years

  • ECG

    • Transient ST-segment deviation >0.5 mm

    • Bundle-branch block, new or presumed new

    • Sustained ventricular tachycardia

  • Cardiac marker

    • Elevated cardiac TnT, TnI, or CK-MB (e.g., TnT or TnI >0.1 ng per ml)

High-risk features were defined as in the ACS guidelines (21).

CK-MB = creatine kinase, MB isoenzyme; ECG = electrocardiogram; MI = myocardial infarction; MR = mitral regurgitation; NSTEMI = non–ST segment elevation myocardial infarction; TnI = troponin I; TnT = troponin T; UA = unstable angina.