Table 4

Revascularization Versus Medical Therapy By Revascularization Stratum and SYNTAX Score

Outcome VariableSYNTAX ScoreAdjusted HR95% CIp ValueInteraction p Value
CABG stratum (N = 577)
 Death/MI/strokeLow (≤22)0.880.58–1.350.560.08
Mid/high (≥23)0.460.25–0.850.01
 DeathLow (≤22)0.900.52–1.580.720.57
Mid/high (≥23)0.700.35–1.410.32
 Cardiac deathLow (≤22)1.030.47–2.290.940.56
Mid/high (≥23)0.720.27–1.890.50
 MILow (≤22)0.800.44–1.450.460.04
Mid/high (≥23)0.210.07–0.640.01
PCI stratum (N = 973)
 Death/MI/strokeLow (≤22)0.960.70–1.340.820.13
Mid/high (≥23)1.690.89–3.190.11
 DeathLow (≤22)1.010.65–1.560.970.13
Mid/high (≥23)2.230.89–5.580.09
 Cardiac deathLow (≤22)1.130.52–2.450.770.22
Mid/high (≥23)3.090.77–12.310.11
 MILow (≤22)0.950.59–1.520.820.23
Mid/high (≥23)1.680.74–3.820.21

IS/IP = insulin sensitizing/ insulin providing; other abbreviations as in Tables 1, 2, and 3.

  • HR for revascularization versus medical adjusted for: IS/IP assignment, age, sex, history of MI, history of CHF, insulin use at baseline, and eGFR <60 ml/min/1.73 m2.

  • Testing hypothesis of equivalence of HRs for revascularization versus medical therapy in the mid/high SYNTAX and low SYNTAX strata.