Table 2

Baseline Characteristics by Revascularization Stratum and SYNTAX Score

CABG StratumPCI Stratum
Low SYNTAX Score (≤22) (n = 370)Mid/High SYNTAX Score (≥23) (n = 207)p ValueLow SYNTAX Score (≤22) (n = 849)Mid/High SYNTAX Score (≥23) (n = 124)p Value
Age at study entry, yrs63.4 (57.9–68.9)64.7 (57.8–70.1)0.19861.2 (55.2–68.2)61.5 (55.5–68.1)0.734
Male74.6 (276)81.6 (169)0.05366.1 (561)74.2 (92)0.072
Race/ethnicity
 White non-Hispanic68.9 (255)75.4 (156)0.42464.1 (544)58.9 (73)0.232
 Black non-Hispanic11.4 (42)8.7 (18)20.3 (172)21.0 (26)
 Hispanic13.8 (51)11.6 (24)10.5 (89)10.5 (13)
 Asian/other non-Hispanic5.9 (22)4.3 (9)5.2 (44)9.7 (12)
Insulin-providing assignment49.5 (183)45.4 (94)0.35149.8 (423)54.8 (68)0.297
Sitting systolic BP, mm Hg132.7 (120.0–147.0)132.0 (120.0–145.3)0.528130.0 (118.0–141.3)128.7 (113.3–142.3)0.580
Sitting diastolic BP, mm Hg76.7 (70.0–82.0)74.7 (68.7–81.3)0.18474.7 (67.3–80.0)71.3 (65.0–79.3)0.095
BMI29.6 (26.7–33.9)30.2 (27.1–33.3)0.48031.9 (28.0–35.7)30.6 (27.2–33.6)0.011
Hypertension requiring therapy83.6 (306)81.7 (165)0.56081.0 (679)78.7 (96)0.541
History of cigarette smoking63.8 (236)66.5 (137)0.51264.2 (543)60.5 (75)0.424
History of MI30.1 (110)34.3 (70)0.30418.1 (151)32.0 (39)0.001
History of CHF requiring therapy4.9 (18)3.9 (8)0.5785.9 (50)4.8 (6)0.631
Duration of DM8.8 (3.5–15.4)8.7 (4.0–15.6)0.5857.8 (3.4–14.1)9.1 (3.9–16.4)0.229
HbA1c %7.40 (6.40–8.80)7.50 (6.50–8.50)0.8197.30 (6.50–8.40)7.20 (6.30–8.20)0.236
LDL, mg/dl95.5 (73.0–122.0)94.0 (75.0–117.0)0.51592.0 (74.0–115.0)90.0 (70.0–123.0)0.937
HDL, mg/dl37.0 (32.0–43.0)36.0 (32.0–42.5)0.98737.0 (31.0–43.0)36.0 (32.0–42.0)0.407
Total cholesterol, mg/dl168.0 (143.0–198.0)167.0 (144.0–192.5)0.422165.0 (141.0–190.0)162.0 (136.0–193.0)0.930
eGFR (MDRD algorithm), ml/min/1.73 m275.7 (63.5–89.7)73.7 (60.2–89.9)0.61678.0 (64.3–92.9)79.7 (63.5–98.2)0.306
Currently taking insulin21.1 (78)21.3 (44)0.97429.4 (249)29.0 (36)0.934
Cerebrovascular accident or TIA7.0 (26)6.4 (13)0.7599.5 (80)14.5 (18)0.082
Chronic renal dysfunction1.9 (7)1.5 (3)0.7092.2 (19)4.1 (5)0.220
Any major ECG abnormalities39.4 (143)33.5 (68)0.16423.4 (192)23.1 (28)0.958
Baseline Q waves15.4 (57)15.0 (31)0.8918.0 (68)7.3 (9)0.772
Baseline ST-segment depression3.2 (12)3.4 (7)0.9291.2 (10)1.6 (2)0.682
Baseline ST-segment elevation6.2 (23)5.8 (12)0.8404.1 (35)4.0 (5)0.962
Site: LVEF <50%15.7 (57)17.6 (36)0.53914.2 (117)20.8 (25)0.059
Number of vessels with lesions ≥50%
 118.1 (67)10.6 (22)0.00157.0 (483)21.0 (26)0.001
 247.3 (175)38.2 (79)30.8 (261)43.5 (54)
 334.6 (128)51.2 (106)12.2 (103)35.5 (44)
Number of lesions5.0 (4.0–7.0)6.0 (5.0–7.0)0.0024.0 (2.0–5.0)5.0 (4.0–6.0)0.001
Lesions ≥50% stenosis3.0 (2.0–4.0)4.0 (3.0–5.0)0.0012.0 (1.0–3.0)3.0 (2.0–4.0)0.001
Myocardial jeopardy57.0 (41.0–74.0)68.0 (52.0–79.0)0.00133.0 (20.0–48.0)55.0 (41.5–72.0)0.001
Proximal LAD ≥50% stenosis14.9 (55)23.2 (48)0.0127.6 (64)13.7 (17)0.021
Total occlusions44.4 (156)55.8 (110)0.01038.5 (5)0.0 (0)0.439

Values are median (interquartile range) or % (n).

CABG = coronary artery bypass graft; PCI = percutaneous coronary intervention; other abbreviations as in Table 1.