Author + information
- Received October 20, 1992
- Revision received February 2, 1993
- Accepted February 9, 1993
- Published online August 1, 1993.
- ↵∗Address for correspondence: Spencer B. King III, MD, Emory University Hospital, Suite P606, 1364 Clifton Road Northeast, Atlanta, Georgia 30322.
Objectives. The objective of this communication was to report the long-term follow-up of all the patients treated by Dr. Andreas Gruentzing in Zurich, Switzerland.
Background. The first patients to undergo percutaneous transluminal coronary angioplasty had the procedure performed by Andreas Gruentzig in Zurich between 1977 and 1980. The method of angioplasty has changed little, and the patients undergoing these first procedures were similar to many patients undergoing angioptasty today; therefore, their long-term outcome is of significant interest.
Methods. All 169 patients with angioplasty during Gruentzig's years in Zurich have now been completely followed up at 10 years. All surviving patients were contacted directly or by telephone interview, and the occurrence of each cardiac procedure and coronary event was analyzed.
Results. One hundred thirty-three of the 169 patients under-went successful angioplasty. Ten-year follow-up of this group revealed an overall survival rate of 89.5%. The survival rate was 95% with single-vessel disease and 81% among those with multivessel disease. Patients undergoing unsucessful dilation and those with failed angioplasty and subsequent bypass surgery had a similar 10-year survival rate. Angiographic restenosis was present in 31% at 6 months. Late restenosis between 6 months and 10 years occurred in eight patients; however, progressive of disease in undilated segments occurred in 31 patients. In addition to a better survival rate, patients with single-vessel disease were less likely to have had bypass surgery and were more likely to be angina free at the 10-year follow-up than were patients with multivessel disease (79% vs. 67%).
Conclusions. This earliest angioplasty experience was also the first to demonstrate a difference in outcome between patients with single-vessel and multivessel disease treated with angioplasty. Although angioplasty is now performed in more complex patient subsets, the long-term outcome of these “classical” angioplasty patients should be applicable to similar patients treated today.
☆ This work was supported in part by USCI, a division of C.R. Bard, Billerica, Massachusetts.
- Received October 20, 1992.
- Revision received February 2, 1993.
- Accepted February 9, 1993.