|Risk Factors (Control Groups)||Relative Risk|
|Previous stroke or TIA||2.5|
|History of hypertension||1.6|
|Heart failure or impaired left ventricular systolic function||1.4|
|Advanced age (continuous, per decade)||1.4|
|Coronary artery disease||1.5|
Adapted from Fuster et al. (4).
↵⁎ Data derived from collaborative analysis of untreated control groups in 5 primary prevention trials (9). As a group, patients with nonvalvular AF have approximately a 6-fold increased risk of thromboembolism compared with patients in sinus rhythm. Relative risk refers to comparison of patients with AF to patients without these risk factors.