Author + information
- David J. Sahn,
- Kacie Amacher,
- Rosie Bleck,
- Meihua Zhu,
- Cole Streiff,
- Sumito Kimura,
- Sreyas Ravi,
- Austin Park and
- Muhammad Ashraf
Published research suggests that 2D speckle tracking can determine regional cardiac strain and therefore be an important index of cardiac function. This study evaluated moving 3D images obtained with a GE Vivid E9 ultrasound system and analyzed by GE 4D EchoPAC against sonomicrometry (sono) in a pumped heart model.
A pulsatile apparatus was used to pump 6 adult pig hearts at physiologic stroke volumes (SV, 30-70 ml) at 5 different degrees of rotation. The hearts were sutured to a latex balloon with the base affixed to a rotating plate and the apex lightly fixed in place. Four sono crystals were sutured, 3 on the epicardium for circumferential and longitudinal strain (CS, LS), and 1 on the endocardium for radial strain (RS). Images were analyzed for strain in the mid anterior segment with EchoPAC semi-automated software, and compared against sono data.
The linear regression comparing sono data to EchoPAC derived strain values resulted in strong correlation coefficients for CS (R2= .60), LS (R2= .65), and RS (R2= .90); P values < 0.001. Bland-Altman analyses showed 90%, 97%, and 90% of points within a 95% confidence interval for CS, LS, and RS, respectively. Bland-Altman plots also show a consistent over-estimation in EchoPAC strain values.
Despite consistent overestimation, the strong correlation suggests that the GE 4D echo with EchoPAC can effectively calculate strain.
Poster Sessions, Expo North
Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Imaging: CRT/New Technology
Abstract Category: 18. Imaging: Echo
Presentation Number: 1312-338
- 2013 American College of Cardiology Foundation