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Atrial Fibrillation (AF) is a known risk factor for stroke. The role of catheter ablation (CA) in modulating the risk of stroke is unknown. We compared the incident rate of stroke in patients undergoing CA to others with AF not treated with CA.
A retrospective cohort study was conducted using the University of Utah Enterprise Data Warehouse (EDW) between January 2006 and October 2012. We compared AF pts undergoing CA to AF pts not undergoing CA. Pts were followed till the end of study period or date of occurrence of stroke whichever came first. Multivariate analysis was performed to assess the likelihood of stroke in the CA groups, adjusting for CHADS2 score and other comorbidities.
A total of 13,751 were included. CA was performed in 1,099 pts (7.4%). The mean age was lower in the CA group (61.8±14.5 yrs) compared to the no-CA group (66.3±14.7yrs; p<0.01). The CHADS2 score was 0.89±1.1 in the CA group compared to 0.65±89 in the no-CA group. Warfarin use was lower in the no-CA group (12.36%) compared to the CA group (31.57%; P<0.01). The incidence of stroke in the no-CA group was significantly higher (n=1,758; 12.78%) in the no-CA group compared to the CA group (n=45; 4.09%; p<0.01). Pts in the CA group had a lower likelihood of stroke (odds ratio [OR], 0.29; 95% confidence interval [95% CI], 0.21-0.40).
Catheter ablation for atrial fibrillation is associated with a lower rate of incident stroke and a higher rate of warfarin use compared to other management strategies.
Moderated Poster Contributions
Poster Sessions, Expo North
Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Atrial Fibrillation Ablation
Abstract Category: 4. Arrhythmias: AF/SVT
Presentation Number: 1278M-38
- 2013 American College of Cardiology Foundation