Author + information
- Gustavo Jardim Volpe,
- Henrique T. Moreira,
- Henrique S. Trad,
- Katherine C. Wu,
- Maria Fernanda B. Santos,
- Marcel K. Santos,
- Benedito C. Maciel,
- Jose Antonio Marin Neto,
- David A. Bluemke,
- Joao A C Lima and
- Andre Schmidt
Chagas Heart Disease (CHD) is related to myocardial fibrosis (MF) and has a well-known relationship with sudden cardiac death (SCD). Cardiac magnetic resonance (CMR) can assess MF.
Evaluate CMR functional parameters and late gadolinium enhancement (LGE) in patients with events in a CHD cohort.
79 patients with CHD disease (56.9% female; 53.2 ± 13.6 years) from Ribeirao Preto Clinical Hospital (Sao Paulo, Brazil) were included, with 5 of them with a previous aborted SCD. A CMR was performed from October/2009 to April/2012, including cines at the long vertical, long horizontal and short axis. LGE sequences were performed after 10.1 ± 1.5 min gadolinium contrast (0.2mmol.kg) in the same cine positions, with the positive cases classified as transmural, focal and diffuse patterns.
During a mean follow-up of 20.7 ± 6.4 months, 4 patients died and were included in the events group with the ones with previous SCD. There was scar in 79.5% of the participants. Higher left ventricular mass and diastolic volume were observed in the events group and the LGE positive without events. Left ventricular ejection fraction was lower in the same subjects. The focal pattern of LGE was the most commonly observed (40.4%), followed by the transmural (32.3%) and the diffuse (27.5%). There was no difference in this parameter among the groups.
Presence of scar is a marker of more severely ill patients and it is related to events in the Chagas heart disease, independent of the pattern on LGE.
Poster Sessions, Expo North
Saturday, March 09, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Imaging: MRI III – CMR in Myocardial Disease and Dysfunction
Abstract Category: 19. Imaging: MRI
Presentation Number: 1184-363
- 2013 American College of Cardiology Foundation