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3D strain echocardiography assesses left ventricular (LV) segmental wall motion and locate ischemic myocardium by analysis of regional strain, but accuracy varies in different analysis programs. This study evaluated vendor specific and independent programs to calculate longitudinal and circumferential strain (LS, CS) against sonomicrometry to assess accuracy and precision and detection of infarction.
Latex balloons were sewn into the LVs of 5 fresh pig hearts and attached to a pulsatile pump. Hearts were pumped at 5 stroke volumes (30-70ml) with constant rotation (5) and compaction (10 mm). Sonomicrometry crystals were sewn onto the epicardiam in triangular formation. Glutaraldehyde was injected to simulate myocardial infarction (Ml). Images were taken before and after Ml, then analyzed by Toshiba's 3D wall motion tracking (3D-WMT) program and TomTec's Research Arena program.
Linear regression analysis showed excellent correlation between 3D-WMT derived strain and sonomicrometry data (CS: R2=0.77, LS: R2=0.76) and Arena derived strain (CS: R2=0.72, LS: R2=0.73), all p<0.05. Bland-Altman analysis revealed comparable values. After Ml induction, LS and CS in 3D-WMT and Arena were significantly decreased, both displaying excellent correlation with sonomicrometry data (R2: 0.64∼0.83, all p<0.001).
Both vendor specific (3D-WMT) and independent (Arena) programs can accurately determine myocardial deformation from 3D echo volumes and detect Ml.
Poster Sessions, Expo North
Sunday, March 10, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Imaging: Echo IX
Abstract Category: 18. Imaging: Echo
Presentation Number: 1227-349
- 2013 American College of Cardiology Foundation