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Heart failure (HF) is a common disease worldwide. On the other hand, regular physical activity is beneficial in terms of outcomes. In this study, parameters which influence regular activity were investigated.
100 consecutive outpatients (age 65±13 years, 54 males, 46 females) with stable systolic heart failure (31±10% ejection fraction) were enrolled. All patients were asked for engagement with regular physical activity, and evaluated with Beck depression inventory (BDI).
41 out of 100 patients stated that they engage regular physical activity with a median of 3 days per week (ranging from 1-7 days/week). In the univariate analysis, absence of regular physical activity was associated with female gender, lower ejection fraction (EF), higher NYHA functional class, nonischemic etiology, presence of therapy with spironolactone, higher BNP, BUN, longer duration of HF, lower plasma sodium, higher tricuspid annular excursion (Table 1). Patients were classified into two as those with presence of at least mild depression (BDI score ≥14) versus those without depression. It was found that at least mild form of depression (BDI ≥14) was found in 36.6% of patients having regular physical activity whereas, depression was present in 88.1% of patients not having regular physical activity. Of note, severe depression (BDI ≥29) was present in 7.3% and 49.2% respectively. Beck depression score was able to predict absence of engagement in regular physical activity in patients with HF (AUC=0.827, p<0.001). In the stepwise regression analysis, it was found that female gender (p=0.010, ExpB=4.251, 95%CI:1.417-12.751), having at least mild depression by BDI (p=0.0.10, ExpB=4.639 95%CI:1.451-14.829) and EF (p=0.017, ExpB=0.928, 95% CI:0.873-0.986) were found to be independent predictors of absence of regular physical activity in stable outpatients with systolic HF.
Depression could potentially influence engagement in regular physical activity in outpatients with systolic HF.