Author + information
- Mislav Vrsalovic,
- Scott Hummel,
- Hamid Ghanbari,
- Craig Alpert,
- Hakan Oral and
- Theodore Kolias
Atrial fibrillation (AF) frequently recurs after radiofrequency catheter ablation (CA). This study investigated novel echocardiographic strain parameters as predictors of outcome in AF treated with CA.
110 patients (mean age 59, mean CHA2DS2-VASc = 1.37) with paroxysmal AF and preserved ejection fraction (EF) underwent CA and echocardiography ≤ 30 days prior to CA (while in sinus rhythm). Left atrial (LA-GS) and left ventricular (LV-GS) global longitudinal strains were measured with 2D speckle tracking. Patients were followed for AF recurrence after CA.
During mean follow-up of 16±6 months, 44 patients (40%) had AF recurrence. LA-GS (dichotomized to > or < 24.5 %) predicted freedom from AF recurrence (p<0.001; Figure 1). Patients with AF recurrence had lower LA-GS (22% vs 31%; p<0.001) and lower magnitude of LV-GS (-15.6% vs -17.4%; p=0.001). ROC analysis revealed that LA-GS predicted AF recurrence better than LV-GS (AUC= 0.87 vs. 0.69; p=0.002) or LAVI (AUC=0.87 vs. 0.59; p<0.001). LA-GS <24.5% had 75% sensitivity and 91% specificity for predicting AF recurrence. By multivariate analysis, LA-GS entered either as a binary (<24.5%) (HR=8.91, 95% CI=4.35-18.27; p<0.001) or a continuous variable (HR=0.88, 95% CI=0.85-0.92; p<0.001) was the only independent predictor of AF recurrence.
Left atrial strain by speckle tracking echocardiography is a strong and independent predictor of AF recurrence after CA therapy in patients with paroxysmal AF and preserved EF.
Poster Hall B1
Sunday, March 15, 2015, 9:45 a.m.-10:30 a.m.
Session Title: Non Invasive Imaging: Strain Imaging by Echocardiography
Abstract Category: 17. Non Invasive Imaging: Echo
Presentation Number: 1174-018
- 2015 American College of Cardiology Foundation