Author + information
- Lv Wenkui,
- Xianhui Zhou and
- Baopeng Tang
This meta-analysis aimed to compare the efficacy and safety of the CF-sensing catheter and second-generation cryoballoon (CB) ablation in treating AF.
The randomized controlled trials (RCTs) or controlled clinical trials (CCTs) comparing the ablation for AF using a CF-sensing catheter or second-generation cryoballoon were identified from PubMed, EMBASE, Cochrane Library, Wanfang Data, and China National Knowledge Infrastructure (January 1, 1998-February 1, 2016).
The duration of procedure [mean difference (MD) = 19.05; 95% CI,?1.41 to 39.50; P = 0.07] and fluoroscopy (MD = 0.75; 95% CI,?4.91 to 6.42; P =0.79) was lower in the CB group compared with the CF group although the results were not significant. The incidence rate of severe non-lethal complications (embolic event, tamponade and esophageal injury) was significantly lower in the CB group compared with that of the CF group (1.65% vs. 4.64%; RR = 2.79; 95% CI, 1.02-7.62; P < 0.05), whereas transient phrenic nerve palsy occurred in 26 of 331 patients (7.9%) of the CB group vs. none in the CF group (RR = 0.07; 95%CI, 0.02-0.29; P < 0.05). A comparable proportion of patients in CF and CB group suffered from AF recurrence during 12 months follow-up after a single ablation procedure [risk ratio (RR) = 1.03; 95%CI, 0.78-1.36; P = 0.84].
AF ablation using CF-sensing catheters and second generation CB ablation showed comparable efficacy during a 12-month follow-up. The mean procedure and fluoroscopy duration was slightly shorter with second generation CB ablation than CF-sensing catheters. Different complications occurred in CF and CB groups, respectively.