Author + information
- Abhishek Sawant,
- Rose Hansen,
- Shannon Baldo and
- Vijay Iyer
Background: Poor quality of life (QOL) after Transcatheter Aortic Valve Replacement (TAVR) has been shown to have adverse outcomes in several studies. However, identifying patients likely to have poor QOL outcomes after TAVR remains challenging.
Methods: We included 335 consecutive patients who underwent TAVR from 2012-15 and completed the baseline Kansas City Cardiomyopathy Questionnaire (KCCQ)-12 survey. Clinical, laboratory, angiographic, QOL and mortality data were obtained.
Results: The mean age of patients was 82 ± 8 years, 49% were males and majority were Caucasians (94%). The median Society of Thoracic Surgeons (STS) risk score was 9 [Range: 3,46]. The majority had hypertension (94%), atrial fibrillation (44%), peripheral arterial disease (40%), and diabetes (38%). The median increase in KCCQ-12 score post TAVR was 48 [Range: 0, 97] points. Poor QOL outcomes (post-TAVR score ≤ 25th-percentile or change ≤ 15 points) occurred in 76/253 (30%) patients and were similar among intermediate and high STS risk groups (27 vs 31%, p=0.50). After adjusting for significant variables, multivariate regression identified history of atrial fibrillation, hemoglobin < 10 gm/dl and discharge to facility other than home after TAVR as key predictors of poor QOL outcomes (Figure 1).
Conclusions: Around one third patients have poor QOL outcomes after TAVR irrespective of preoperative STS risk. Use of predictive models to identify these patients can help improve QOL outcomes but require future prospective evaluation.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Interventional Cardiology: TAVR 4
Abstract Category: 17. Interventional Cardiology: Aortic Valve Disease
Presentation Number: 1283-136
- 2017 American College of Cardiology Foundation