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Background: Two-dimensional (2D) echocardiography has been widely used to assess right ventricular systolic function in atrial septal defect (ASD). However, there are limitations in 2D methods considering the complex anatomy and chamber shape of the right ventricle. Real Time three-dimensional echocardiography (RT3D) is a newly introduced echocardiographic method with the advantage of displaying the 3D structure of the chamber. Therefore this study is To evaluate regional and global right ventricular (RV) systolic function in patients with ASD before and after percutaneous closure using three-dimensional echocardiography (3DTEE).
Methods: 3DTEE was performed in 120 patients with ASD within 24 hours before and after percutaneous closure to obtain regional and global RV ejection fraction (EF) in three regions (inflow, outflow and body). RV fractional area change (FAC), tricuspid annular plane systolic excursion (TAPSE), peak tricuspid systolic velocity (S), and pulmonary vascular resistance (PVR) were recorded. 60 matched normal adults were included as controls.
Results: When compared with controls, RV regional and global EF were decreased in preclosure patients (P < 0.005). FAC was lower while TAPSE and S were higher in preclosure patients than in controls (P < 0.01). After closure, RV systolic function parameters were all reduced (P < 0.005). Regional EF in the body compartment was the lowest among the three regions in ASD patients (P < 0.05). Procedural percentage changes of RV global EF and regional EF in the inflow compartment were lower than those of two-dimensional systolic function parameters (P < 0.01). RV regional and global EF in the inflow compartment were negatively correlated with PVR in patients after closure (r = -0.7, -0.617, P < 0.005).
Conclusions: RV regional and global systolic functions are impaired in open and closed ASD. 3DTEE derived systolic function parameters are negatively correlated with RV after load. 3DTEE has good value in the evaluation of RV systolic function in patients with ASD.
Poster Hall, Hall C
Friday, March 17, 2017, 10:00 a.m.-10:45 a.m.
Session Title: Novel Echocardiographic Methods for Assessing Cardiac Function
Abstract Category: 28. Non Invasive Imaging: Echo
Presentation Number: 1120-228
- 2017 American College of Cardiology Foundation