Author + information
- Philip Brainin,
- Sune Pedersen,
- Morten Sengeløv,
- Flemming Javier Olsen,
- Thomas Hansen,
- Jan Jensen and
- Tor Biering-Sorensen
Background: Following an ischemic event post systolic shortening (PSS) may occur. We investigated the association between PSS in patients with ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI) and the occurrence of cardiovascular events at follow-up.
Methods: A total of 375 patients admitted with STEMI and treated with primary PCI were prospectively included in the study cohort. All patients were examined by echocardiography a median of 2 days after admission (interquartile range, 1-3 days). PSS was measured by color tissue Doppler imaging (TDI) in six myocardial walls from all three apical projections.
Results: During a median follow-up period of 5.4 years (interquartile range, 4.1-6.0 years), 179 events occurred: 59 deaths, 70 heart failures (HF) and 50 new myocardial infarctions.
In multivariable analysis, presence of PSS in the culprit region was associated with a nearly twofold increased risk of HF (HR 1.90, 95% CI 1.02-3.53, P=0.043) and the risk of HF increased incrementally with increasing numbers of walls displaying PSS (figure). A regional analysis showed that PSS in the septal wall was the strongest predictor of HF (HR 1.77, 95% CI 1.08-2.92, P=0.024). Presence of PSS was not associated with increased risk of neither death nor MI.
Conclusions: In patients with STEMI treated with PCI, the presence of PSS examined by TDI provides prognostic information on development of HF. Presence of PSS in the septal wall was the strongest predictor of HF.
Poster Hall, Hall C
Saturday, March 18, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Innovative Use of Echocardiography
Abstract Category: 28. Non Invasive Imaging: Echo
Presentation Number: 1197-222
- 2017 American College of Cardiology Foundation