Author + information
- Blanca Trejo Velasco,
- Oscar Fabregat-Andrés,
- María Pilar García-González,
- Mónica Ferrando,
- Diana Perdomo-Londoño,
- Cristina Albiach-Montañana,
- Rafael dela Espriella-Juan,
- Sergio Sánchez-Álvarez,
- Juan Pablo Cárdenas-Tealdo,
- Salvador Morell-Cabedo and
- Francisco Ridocci-Soriano
Background: Pulmonary hypertension (PH) associated with heart failure with reduced ejection fraction (HFrEF) conveys a worse outcome in this high risk population. Evaluation of right ventricular (RV) function further stratifies the prognosis. Cardiac magnetic resonance (CMR) has emerged as a useful non-invasive technique for the evaluation of PH, as it provides accurate information on pulmonary vascular status and RV size and function.
Methods: We prospectively included 204 patients admitted for new-onset HFrEF with CMR study during index admission. Patients were stratified according to mean pulmonary artery velocity (mPAv) values based on ROC curve results for the prediction of cardiovascular events: readmission for heart failure and cardiovascular death. A multivariate Cox regression model and Kaplan-Meier survival curves were performed.
Results: No differences between baseline characteristics according to mPAv values were found. At a mean follow-up of 16±15 months, patients with mPAv values < 9cm/s had a significant worse prognosis, independently of RV function, as indicated by Kaplan-Meier survival curves (Figure 1). Moreover, mPAv values < 9cm/s independently predicted cardiovascular events in Cox regression analysis.
Conclusions: mPAv predicts adverse cardiovascular events in patients with HFrEF, irrespective of RV ejection fraction. mPAv could be an early prognostic indicator as it identifies a high risk subset of patients before development of RV dysfunction.
Poster Hall, Hall C
Saturday, March 18, 2017, 3:45 p.m.-4:30 p.m.
Session Title: Non Invasive Imaging: MR Scar and Perfusion
Abstract Category: 29. Non Invasive Imaging: MR
Presentation Number: 1244-203
- 2017 American College of Cardiology Foundation