Author + information
- Christoffer Goransson,
- Niels Vejlstrup and
- Jorn Carlsen
Background: Right ventricular stroke volume (SV) is measured with flow cardiovascular magnetic resonance (CMR) imaging in the main pulmonary artery (MPA). Measuring SV in branch pulmonary arteries (PB) with laminar flow may more accurately assess right ventricular SV due to turbulence in the main pulmonary artery (MPA). This study compared SV measurements in the PB with SV in the MPA and left ventricle (LV) in pulmonary arterial hypertension (PAH).
Methods: SV was measured in the PB and MPA by CMR flow in 18 patients with PAH and 10 controls. LV SV was measured by CMR cine covering the LV in the short axis plane. Paired t-test and test for correlation (R) was used as well as assessment of variance (R2).
Results: PB SV reflected LV SV in both the PAH group (p=0.36) and control group (p=0.14). The control group had better correlation and lower variance (PAH, R=0.75 [R2=0.56]; Controls, R=0.97 [R2=0.94]. PB SV was higher than MPA SV in both groups (PAH 7% [CI 0-15%], p=0.05; Controls 3% [CI, 1-5%], p=0.01) with better correlation and lower variance in the control group (PAH, R=0.83 [R2=0.70]; Controls, R=0.99 [R2=0.98]). MPA SV was lower than LV SV in both groups (PAH 11% [CI 6-15%], p=0.0002; Controls 5% [CI 1-10%]), p=0.03. See Figure.
Conclusions: RVSV in PAH should be measured by flow in the branch pulmonary arteries rather than by MPA flow leading to a more accurate assessment of the pulmonary circulation.
Poster Hall, Hall C
Sunday, March 19, 2017, 9:45 a.m.-10:30 a.m.
Session Title: Advances in Pulmonary Arterial Hypertension
Abstract Category: 35. Pulmonary Hypertension and Pulmonary Thrombo-embolic Disease
Presentation Number: 1269-008
- 2017 American College of Cardiology Foundation