Author + information
- Keiko Mizobuchi,
- Kentaro Jujo,
- Yuichiro Minami,
- Issei Ishida,
- Shintaro Haruki,
- Hiromu Kadowaki,
- Kazuki Tanaka,
- Madoka Akashi,
- Motoko Kametani,
- Masashi Nakao,
- Jyunichi Yamaguchi and
- Nobuhisa Hagiwara
The CONUT (CONtrolling NUTritional) score is simple index calculated from the following factors; serum albumin concentration, total peripheral lymphocyte count and total cholesterol concentration, and has been reported to well represent nutritional status in hospitalized patients. We aimed to determine prognostic value of CONUT score in patients with peripheral artery disease (PAD).
This study included 599 consecutive patients who received endovascular therapy (EVT) between 2013 and 2016. Patients were divided into 4 groups based on CONUT score: low risk (score 0: n=73), mild risk (score 1-2: n=265); moderate risk (score 3-4: n=197) and high risk (score >/=5: n=64). The primary endpoint of this study was major amputation-free survival (AFS).
Higher CONUT class included patients with higher rates of chronic kidney disease (CKD) and critical limb ischemia (CLI). During the follow-up period, 64 deaths (11%) and 33 major amputations (6%) were observed. Kaplan-Meier analysis of the 4 subgroups revealed that patients with higher CONUT class had the higher risk for AFS (log-rank: p<0.001, Figure). In univariate Cox regression analysis, higher CONUT class had a significantly higher hazard ratio (HR) of AFS. This finding retained significance even after adjustment for age, gender and morbidity of CKD and CLI (HR: 1.92, 95% confidence interval: 1.47-2.51).
CONUT score may predict long-term adverse clinical events after EVT in PAD patients.
Poster Hall, Hall A/B
Sunday, March 11, 2018, 9:45 a.m.-10:30 a.m.
Session Title: Endovascular Intervention and Renal Denervation
Abstract Category: 18. Interventional Cardiology: Carotid and Endovascular Intervention
Presentation Number: 1197-261
- 2018 American College of Cardiology Foundation