Evolution of LV Diastolic Parameters With Increasing Disease Severity
Some parameters pseudonormalize, others change late in the disease, or change early and do not progress. LA strain appears to progressively worsen with increasing severity. Moreover, the addition of LA strain may allow more accurate judgment of disease stage. Although cutoffs vary within the published reports and between laboratories, the relative changes are consistent. LA = left atrial; LAVi = indexed left atrial volume; LV = left ventricular.