Author + information
- Giovanna Valentino,
- Rodrigo Tagle,
- Jorge Quitral,
- Lorena Orellana,
- Marcela Adasme,
- Pamela Illanes,
- Fernando Baraona,
- Carlos Navarrete and
- Monica Acevedo
Last National Chilean Health Survey (NHS) has shown that the mean salt intake was 9 gr/day. Sodium intake is directly associated with higher blood pressure (BP). Potassium intake attenuates the hypertensive effect of salt.
To determine the predictive power of urinary sodium/potassium ratio (Nau/Ku) and salt intake on the progression from normal to normal-high BP and hypertension (HTN) stage 1 or 2.
4780 subjects (NHS 2009) were included. Daily salt intake and Nau/Ku ratio was calculated using a morning isolated urinary sample. HTN was determined according to European guidelines (ESC 2018): high normal BP: ≥130 / 80; HTN-1: ≥140/90 and HTN-2: ≥160/100 mm hg and the AHA/ACC HTN guidelines 2017: elevated BP: ≥120 and 80; HTN-1: ≥130/80 and HTN-2: ≥140/90 mmHg. Proportional odds models were built to determine the probability of progressing from normal to high BP, HTN-1 and 2 according to Nau/Ku ratio and salt intake (adjusted for age/sex/BMI).
Mean age was 42 yo; 60% women; 25% HTN by ESC 2018 and 44% by AHA/ACC 2017. Average salt intake was 10 gr/d and mean Nau/Ku ratio = 4 ± 2. Adjusted models showed that Nau/Ku ratio was a better predictor of normal-high BP progression to HTN-1 and 2 than salt intake (OR = 1.09 vs 1.07; p <0.01 respectively); effect was greater in women. See figure.
Nau/Ku ratio is a better predictor of BP progression compared to daily salt intake. This data underscore that potassium intake may counteract the hypertensive effect of a high daily sodium consumption.
Poster Hall, Hall F
Saturday, March 16, 2019, 10:00 a.m.-10:45 a.m.
Session Title: Prevention: Hypertension 1
Abstract Category: 33. Prevention: Hypertension
Presentation Number: 1132-416
- 2019 American College of Cardiology Foundation