Author + information
- Mariam Khandaker,
- Zuhair Khandker,
- Bing Yue and
- Fazila-Tun-Nesa Malik
Some studies suggest that patients receiving influenza vaccination have fewer instances of myocardial infarction (MI). We utilized the 2014 United States' National Inpatient Sample (NIS) database to study the relationship between influenza vaccination and prevalence of MI.
This was a retrospective cohort study of all adult patients in the 2014 NIS database. The patients were divided into those who received influenza vaccination in 2014 (defined by the corresponding ICD-9-CM diagnosis code) and those who did not. The primary outcome was MI, including both ST- and non-ST-segment elevation MI as well as unstable angina. A multivariate regression analysis was performed to compute the adjusted odds ratio (AOR) for MI, controlling for age, gender, ethnicity, socioeconomic status, insurance category, as well as hospital size, location, and type.
The study included 29,763,704 adult patients. The raw data showed a lower prevalence of MI in vaccinated patients (3.4% vs. 4.4%). Adjusting for the confounding variables listed above, the AOR for MI was computed to be 0.91 (95% confidence interval 0.87-0.96) in vaccinated patients compared to non-vaccinated ones.
In the 2014 NIS database, adult patients with influenza vaccination were associated with a statistically significantly lower prevalence of MI compared to non-vaccinated patients. This is consistent with other initial studies and suggests that influenza vaccination may be useful as a preventative measure for MI.
Moderated Poster Contributions
Acute and Stable Ischemic Heart Disease Moderated Poster Theater, Poster Hall, Hall F
Saturday, March 16, 2019, 3:45 p.m.-3:55 p.m.
Session Title: The Best Health Services Research Abstracts in CAD
Abstract Category: 02. Acute and Stable Ischemic Heart Disease: Clinical
Presentation Number: 1009-03
- 2019 American College of Cardiology Foundation