Author + information
- Mads Ørbæk Andersen,
- Søren Zöga Diederichsen,
- Jesper Hastrup Svendsen and
- Jorn Carlsen
Arrhythmias are considered a prominent phenomenon in pulmonary hypertension (PH) as the disease progresses. According primarily to retrospective studies with up to 24 hours of monitoring, supraventricular tachycardia (SVT) can be found in 8–35% of patients, with significant impact on survival.
Patients diagnosed with PH were included in this prospective single-centre study. Patients received a Reveal LINQ (Medtronic) insertable cardiac monitor (ICM). ICMs continuously monitor the heart rhythm for arrhythmias according to algorithms.
Twenty-four patients were included, of whom 20 patients had pulmonary arterial hypertension (PAH) and 4 had chronic thromboembolic pulmonary hypertension, treated according to Table 1. During 164 patient-months of continuous monitoring (median: 207 days per patient) no long-lasting arrhythmias were observed, but only transient SVTs in one patient lasting a total of 2.5 days. Two had SVTs lasting 4.5 hours, and two hours. Five patients had isolated episodes of SVTs lasting 0–10 minutes and two patients had an episode of bradycardia for 10 seconds. The total arrhythmic burden was a period prevalence of less than 0.001%, despite a RVEF of 20.3% and 35,7% in WHO FC IV and III, respectively.
This is the first study with long-term continuous rhythm monitoring in patients with PH. In contrast to earlier observations no long-lasting arrhythmias occurred during 164 patient-months with a period prevalence as low as less than 0.001%.
|World Health Organization functional class||Patients, n (%)||Arrhythmias (incidence/period prevalence) (%)||PAH therapy, n Mono/ Double/ Triple/Untreated|
|I||5 (20,8)||4.1 %/< 0.0001%||1/ 0/ 3/ 0|
|II||8 (33.3)||16.6 %/< 0.0001%||2/ 4/ 2/ 1|
|III||8 (33.33)||50 %/0.01875 %||3/ 1/ 4/ 0|
|IV||3 (12.5)||0%/0%||1/ 0/ 2/ 0|
Moderated Poster Contributions
Congenital Heart Disease and Pulmonary Hypertension Moderated Poster Theater, Posters, Hall A
Saturday, March 28, 2020, 1:00 p.m.-1:10 p.m.
Session Title: A Potpourri of Interesting Topics in Pulmonary Hypertension
Abstract Category: 35. Pulmonary Hypertension
Presentation Number: 1014-07
- 2020 American College of Cardiology Foundation