Author + information
- Adham Karim,
- Matthew Lacey,
- Jun Li,
- Herbert D. Aronow,
- Eric Secemsky and
- Mehdi Shishehbor
Critical limb ischemia (CLI) carries significant mortality and morbidity, including major amputation, despite the development of effective advanced therapies. The association between malnutrition, a prevalent comorbidity in this population, and outcomes is not well characterized.
Using the 2012 to 2015 National Inpatient Sample, we identified all CLI admissions. A CLI Nutritional Risk Score (CLI-NRS) for patients with a strong likelihood of malnutrition was constructed. The population was divided into 3 groups according to nutritional status (ICD-9, CLI-NRS, or neither). Using multivariable logistic regression, we related nutritional status to inpatient mortality and major amputation.
Of the 1,414,265 hospitalizations associated with CLI, 152,620 (10.8%) patients carried a diagnosis of malnutrition while 336,985 (23.8%) patients were deemed malnourished as per the CLI-NRS. Malnutrition was strongly associated with mortality and morbidity, including major amputation (Table I). Surgical revascularization for malnourished patients was associated with higher mortality than an endovascular approach (5.4% vs 3.4%, p <0.001; adjusted OR 1.211 [1.065 - 1.377]).
Malnutrition is prevalent amongst patients with CLI and is associated with higher likelihood of in-hospital mortality and major amputation. Assessment of nutritional status is critical and should be considered when developing revascularization strategies for this patient population.
Moderated Poster Contributions
Valvular Heart Disease and Vascular Medicine Moderated Poster Theater, Posters, Hall A
Saturday, March 28, 2020, 1:15 p.m.-1:25 p.m.
Session Title: On the Cutting Edge in Peripheral Artery Disease
Abstract Category: 40. Vascular Medicine: Non Coronary Arterial Disease
Presentation Number: 1019-09
- 2020 American College of Cardiology Foundation