Author + information
- Evangelos Oikonomou,
- Sotirios Tsalamandris,
- Georgia Vogiatzi,
- Panagiotis Theofilis,
- Athina Goliopoulou,
- George Lazaros,
- Evagelia Christoforatou,
- Christos Chasikidis,
- Vasiliki Mistakidi,
- Maria Anastasiou,
- Nikolaos Galiatsatos,
- Margenti Papakonstantinou and
- Dimitris Tousoulis
Sleep is an essential physiological process and disturbance of sleep duration may be associated with atherosclerosis.
The Corinthia study is a cross sectional epidemiological study based on 2043 inhabitants of Corinthia region in Greece. Ultrasonography was used to measure intima media thickness (IMT) and the mean IMT (mIMT) was considered a representative of carotid atherosclerosis burden. Thickness of IMT>1.5 mm or protrusion >50% compared to adjacent segments was defined as atherosclerotic plaque. Total sleeping time per day was recorded via surveys. Sleep duration was categorized as normal (NSD, 6-8h), long (LSD, >8h) and short (SSD, %<6h).
Subjects with NSD had less prevalence of diabetes mellitus (p=0.001) but there was no difference in other cardiovascular risk factors. Interestingly, mIMT (SSD: 1.07±0.5 mm vs. NSD: 0.98±0.43 mm vs. LSD: 1.07±0.53 mm, p=0.001) and carotid atherosclerotic plaque (SSD: 30% vs. NSD: 23% vs. LSD: 29%, p=0.016) were decreased in NSD subjects (Figure). After adjustment for known confounders, regression analysis revealed that subjects with SSD and LSD have 54% and 39% increased odds respectively of carotid atheromatic plaque than those with NSD (Figure).
A balanced sleeping duration of 6-8h daily can act as an additive cardioprotective factor in the modern western type societies. Short and long sleep duration may act as a cardiovascular risk factor.
Posters Hall_Hall A
Sunday, March 29, 2020, 3:45 p.m.-4:30 p.m.
Session Title: Prevention: Clinical 6
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1360-87
- 2020 American College of Cardiology Foundation