Author + information
- Demosthenes Panagiotakos,
- Matina Kouvari,
- Christina Chrysohoou,
- Ekavi Georgousopoulou,
- Dimitrios Tousoulis and
- Christos Pitsavos
Plant-based dietary patterns have been widely promoted for cardiovascular disease (CVD) risk reduction. Nonetheless, not all plant-based diets are equally healthy. The association between plant-based diet indices and 10-year fatal/non fatal cardiovascular disease incidence in apparently healthy men and women was evaluated.
A prospective study was conducted during 2001-2012 studying n=1,514 males and n=1,528 females (aged >18 years old) free of CVD. Follow-up CVD assessment (2011-2012) was achieved in n=2,020 participants (n=317 cases). Overall, healthful and unhealthful plant-based dietary indices (PDI, hPDI and uPDI) were created through a standard procedure; hPDI was principally characterized by increased consumption of fruits/vegetables, whole grains, nuts, legumes, oils, tea/coffee while uPDI was related with increased intake of juices, sweetened beverages, refined grains, potatoes and sweets.
Ranking from 1st to 3rd PDI tertile, CVD event was for men, 24%, 17% and 12% (p=0.002) and for women, 14%, 10% and 9% (p=0.06). Multiadjusted analysis revealed significant inverse associations between PDI and CVD event for men [Hazard Ratio (HR) (3rd vs. 1st tertile)=0.75 95% Confidence Interval (95%CI) (0.60, 0.92)] and -borderline significantly- for women [HR(3rd vs. 1st PDI tertile)=0.89 95%CI (0.75, 1.01)]. When the indices for quality of plant-based patterns were used (hPDI and uPDI), only participants assigned to the higher level of adherence to healthful plant-based pattern were significantly protected against CVD onset with this relation being stronger in case of women; [HR(3rd vs. 1st hPDI tertile)=0.68 95%CI (0.56, 0.95), for women] and [HR(3rd vs. 1st hPDI tertile)=0.87 95%CI (0.76, 1.05), for men]. Similarly, the aggravating effect of high adherence to less healthful plant-based food choices was higher for women [HR(3rd vs. 1st uPDI tertile)=1.35 95%CI (1.10, 1.82)].
Higher adherence to plant-based dietary pattern was associated with substantially lower risk for cardiac health while, most importantly, the healthy or unhealthy food choices within this pattern seemed to equally determine long-term CVD risk, yet mainly in women.
Posters Hall_Hall A
Saturday, March 28, 2020, 12:30 p.m.-1:15 p.m.
Session Title: Prevention: Clinical 2
Abstract Category: 32. Prevention: Clinical
Presentation Number: 1161-106
- 2020 American College of Cardiology Foundation