Mortality in Patients With Atrial Fibrillation Receiving Nonrecommended Doses of Direct Oral Anticoagulants
Alan John Camm, Frank Cools, Saverio Virdone, Jean-Pierre Bassand, David Andrew Fitzmaurice, Keith Alexander Arthur Fox, Samuel Zachary Goldhaber, Shinya Goto, Sylvia Haas, Lorenzo Giovanni Mantovani, Gloria Kayani, Alexander Graham Grierson Turpie, Freek Willem Antoon Verheugt, Ajay Kumar Kakkar and for the GARFIELD-AF Investigators∗
Unadjusted and Adjusted Hazard Ratios at 2 Years After Enrollment by Direct Oral Anticoagulant Dosing
The reference category is patients prescribed with the recommended dosing at enrollment. Hazard ratios were adjusted for age, sex, ethnicity, type of AF, diabetes, hypertension, history of bleeding, prior stroke/TIA/SE, congestive heart failure, vascular disease, smoking, and heavy alcohol consumption. AF = atrial fibrillation; SE = systemic embolism; TIA = transient ischemic attack.